So, after releasing gPodder 0.10.0, which has now only one strict dependency on a pure Python module (feedparser), I wanted to try out if I could get gPodder running on Windows (I have tried it once before, but back then I was spawning a wget process to do the actual downloading, which was kind of awkward on the Windows platform).
What you need to get this working is Alberto Ruiz' All-in-one PyGTK Win32 installer and a check-out of the current SVN trunk head of gPodder. To check out a working copy from a Subversion repository on Win32, you can use TortoiseSVN.

I've found some divide-by-zero errors that I didn't see happening on Linux, so I could quickly fix them in our Subversion repository. I also got rid of some old symlinking code that I didn't use anymore, because symlinks on Windows isn't really possible (except for Vista maybe). Other than that, there were just some minor problems with my code being Unix/X11-specific, for example I'm checking for the $DISPLAY variable in the main script, which isn't needed on Win32.
There were other minor annoyances which I haven't dealt with yet, but which don't interfere with the basic functionality of gPodder:
- Running .mp3 or .avi files with the preferred media player (how do I do that on Win32?)
- Getting a GTK Icon Theme into my GTK installation, so all icons in gPodder display properly
- Removing the GUI for iPod synchronization (or get libgpod + Python bindings working on Win32)
- Testing, testing testing :)